𝕙ttps://docs.google.com/presentation/d/16aMKkcAX1QifQabgBSBR_xr8LuoLwnsj9eEBFXi6EYk/edit?usp=sharing […] See slides Read more →

𝕙ttps://docs.google.com/presentation/d/1fXQYo1sXa_FkiisLrd5CjusMkL_42XTG/edit?usp=sharing&ouid=100565019341850449624&rtpof=true&sd=true […] See slides Read more →

𝕙ttps://docs.google.com/presentation/d/11oe2nZIFqs9TOXT_QDqdpsFhZYJeVVLm/edit?usp=sharing&ouid=100565019341850449624&rtpof=true&sd=true […] See slides Read more →

𝕙ttps://docs.google.com/presentation/d/1I0-4u_6PAG5Q9LNi3mfQNnvZsVgf16tO/edit?usp=sharing&ouid=100565019341850449624&rtpof=true&sd=true Read more →

𝕙ttps://docs.google.com/presentation/d/1VYfx0coU5HKQLXwbo5yr7XvgJeqt8Hdf/edit?usp=sharing&ouid=100565019341850449624&rtpof=true&sd=true Read more →

𝔽ind the slides here […] See the vignette here […] Storey, John D., and Robert Tibshirani. 2003. “Statistical Significance for Genomewide Studies.” Proceedings of the National Academy of Sciences 100 (16): 9440–45. Read more →

𝔻ownload powerpoint from here https://uchicago.box.com/s/hwktymdc2nxlcpqik7alk9m6tsypd3c4 […] Sud, A., Kinnersley, B. & Houlston, R. Genome-wide association studies of cancer: current insights and future perspectives. Nat Rev Cancer 17, 692–704 (2017). https://doi.org/10.1038/nrc.2017.82 … Read more →

𝕊ud et al (see reference section). This review covers most of the concepts we want to cover in this class. We will learn by doing and unpack many of the concepts mentioned in the review. Hopefully, you will re-read the paper at the end of the class and realize how much you have learned. […] … Read more →

𝕋he slides can be found [in this link] (https://www.icloud.com/keynote/0Z_tcX5NElsNKIDL3gs0llnUQ#Post-GWAS-MR) Read more →

𝔽ind the class notes here […] Notice that, under the null hypothesis, the estimated effect size divided by the standard error behaves like a normal(0,1) random variable when the sample size is large enough: […] \[ Z = \frac{\hat\beta}{\text{se}(\hat\beta)}\] \[Z \approx N(0,1) ~~~~~~ … Read more →