𝕙ttps://www.icloud.com/keynote/0_qyvjHjowGtOqZd10GD470hA#L5-Population-Structure-PCA […] Mills, Melinda C.; Barban, Nicola; Tropf, Felix C.. An Introduction to Statistical Genetic Data Analysis (p. 237). MIT Press. Kindle Edition. […] J. Novembre, et al “Genes mirror geography within … Read more →

𝕊ee the vignette here Read more →

𝕙ttps://www.icloud.com/keynote/0dwLzjUpbNc3nVNxdrkvM-UHw#L3-Cancer-GWAS-QC (it takes a couple of minutes to set up the access the first time) […] Bycroft, C., Freeman, C., Petkova, D. et al. The UK Biobank resource with deep phenotyping and genomic data. Nature 562, 203–209 (2018). … Read more →

𝕊ud et al (see reference section). This review covers most of the concepts we want to cover in this class. We will learn by doing and unpack many of the concepts mentioned in the review. Hopefully, you will re-read the paper at the end of the class and realize how much you have learned. Read more →

𝔾WAS: \(\boldsymbol{Y} = \boldsymbol{X}\beta + \boldsymbol{\epsilon}\) Example with n=4 \[\begin{bmatrix} y_1 \\ y_2 \\ y_3 \\ y_4 \end{bmatrix} = \begin{bmatrix} x_1 \\ x_2 \\ x_3 \\ x_4 \end{bmatrix}\cdot \beta + \begin{bmatrix} \epsilon_1 \\ \epsilon_2 \\ \epsilon_3 \\ \epsilon_4 \end{bmatrix}\] … Read more →