Posts

Maximum Likelihood Estimation

2021-04-01 Haky Im
𝕄aximum likelihood estimation is one of the most important tools for statistical inference and is used to find estimates for model parameters. […] Download the slides here […] Check out the FiveMinuteStats series here Read more →

Winner's curse

2021-04-01 Haky Im

Genotype Imputation

2021-03-30 Haky Im

Lecture 2 - GWAS of cancer risk

2021-03-30 Haky Im
𝕊ud et al (see reference section). This review covers most of the concepts we want to cover in this class. We will learn by doing and unpack many of the concepts mentioned in the review. Hopefully, you will re-read the paper at the end of the class and realize how much you have learned. Read more →

L1-female-birth-rate

2021-02-18 R package build
𝕎e are told that 241,945 girls and 251,527 boys were born in Paris from 1745 to 1770. y = 241945 n = 241945 + 251527 posterior = function(theta) dbeta(theta,shape1 = y+1, shape2 = n- y + 1) curve(posterior,from = 0,to = 1, main=paste("n = ",n,"; y = … Read more →

L1-miscel

2021-02-18 R package build

L1-theta-male

2021-02-18 R package build
𝕟 = 10 y = 8 likefun = function(theta) {theta^y * (1 - theta)^(n-y)} curve(likefun,from = 0,to = 1, main=paste("n = ",n,"; y = ",y),xlab="theta", ylab="likelihood") abline(v=y/n,col='gray') What if we got 10 heads? n = 10 y = 10 likefun = … Read more →

L3-Bonferroni

2021-02-18 R package build
𝕒lpha = 0.05 Patleastonemistake = function(m) {1 - (1-alpha)^m} curve(Patleastonemistake,from = 1, to=100, ylab="Prob at least one wrong", xlab="m = number of tests") grid() abline(h=1,col='gray') Read more →

L3-Crohns-Additive

2021-02-18 R package build

L4-power

2021-02-18 R package build
𝕝ibrary(tidyverse) ## ── Attaching packages ─────────────────────────────────────── tidyverse 1.3.0 ── ## ✓ ggplot2 3.3.3 ✓ purrr 0.3.4 ## ✓ tibble 3.0.5 ✓ dplyr 1.0.3 ## ✓ tidyr 1.1.2 ✓ stringr 1.4.0 ## ✓ readr 1.4.0 ✓ forcats 0.5.0 ## ── Conflicts ────────────────────────────────────────── … Read more →