Lecture 5 - Population Structure - PCA

Haky Im

2022-04-11

Categories: Lecture

Learning Objectives

  • Identify effects of population structure on GWAS
  • Interpret principal components of the genotype matrix
  • Correct for population structure

Slides

https://docs.google.com/presentation/d/1VYfx0coU5HKQLXwbo5yr7XvgJeqt8Hdf/edit?usp=sharing&ouid=100565019341850449624&rtpof=true&sd=true

References

  • J. Novembre, et al “Genes mirror geography within Europe,” Nature, vol. 456, no. 7218, pp. 98–101, Aug. 2008.

Reuse

Text and figures are licensed under Creative Commons Attribution CC BY 4.0. The source code is licensed under MIT.

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Citation

For attribution, please cite this work as

Haky Im (2022). Lecture 5 - Population Structure - PCA. BIOS 25328 Cancer Genomics Class Notes. /post/2022/04/11/lecture-5-population-structure-pca/

BibTeX citation

@misc{
  title = "Lecture 5 - Population Structure - PCA",
  author = "Haky Im",
  year = "2022",
  journal = "BIOS 25328 Cancer Genomics Class Notes",
  note = "/post/2022/04/11/lecture-5-population-structure-pca/"
}